Background：NEFH,also named as KIAA0845 and NFH,Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton,and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins： L,M,and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE：NF-L,65-68kd; NF-M,145-160kd and NF-H,200-220kd. This antibody recognize NEFH only.
仕様
Synonyms：200 kDa neurofilament protein,CMT2CC,Nefh,Neurofilament heavy polypeptide 200kDa,Neurofilament heavy polypeptide,Neurofilament triplet H protein,NF H,NF-H,NFH,NFH
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：0.54 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse NF200
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：500-1：1000
Swissprot：P19246,P16884
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
