Background:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. It contains 3 Tau/MAP repeats. Phosphorylated at serine residues in K-X-G-S motifs by causing MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), detachment from microtubules, and their disassembly.
仕様
Synonyms:DKFZp686I2148,MAP 2,MAP dendrite specific,MAP-2,MAP2,MAP2A,MAP2B,MAP2C,Microtubule associated protein 2,Microtubule-associated protein 2,MTAP2.
Host:Rabbit
Reactivity:Mouse,Rat
Applications:IHC
Concentration:0.91 mg/mL
Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse MAP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Dilution:IHC 1:500-1:1000
Swissprot:P20357,P15146
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells