Background：This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
仕様
Synonyms：Acetyl CoA choline O acetyltransferase,Acetyl CoA：choline O acetyltransferase,Chat,CHOACTase,Choline acetylase,choline acetyltransferase,Choline O acetyltransferase,Choline O-acetyltransferase,CLAT,CMS1A,CMS1A2,EC 2.3.1.6,OTTHUMP00000019583,OTTHUMP00000019584
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC
Concentration：350 ug/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse CHAT
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
