Background：This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain （ITGB2） to form a leukocyte-specific integrin referred to as macrophage receptor 1 （'Mac-1'）, or inactivated-C3b （iC3b） receptor 3 （'CR3'）. The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：antigen CD11b （p170）,Antigen CD11b p170,CD11 antigen like family member B,CD11 antigen-like family member B,CD11b,CD11b/CD18,CD49d,Cell surface glycoprotein MAC-1 subunit alpha,Complement component 3 receptor 3 subunit,Complement Component Receptor 3 Alpha,Complement receptor type 3,alpha subunit,CR 3 alpha chain （CR3A）,CR 3 alpha chain,CR-3 alpha chain,CR3,CR3A,F730045J24Rik,Integrin Alpha M,Integrin alpha M chain,Integrin alpha-M,Integrin beta 2 alpha subunit,Integrin subunit alpha M,integrin,alpha M （complement component 3 receptor 3 subunit）,ITAM,ITGAM,Leukocyte adhesion receptor MO1,Ly-40,MAC 1,Mac-1a,MAC1,Mac1,alpha subunit,MAC1A,Macrophage antigen alpha polypeptide,MGC117044,Mo1,alpha subunit,MO1A,Neutrophil adherence receptor alpha M subunit,Neutrophil adherence receptor,SLEB6
Host：Rabbit
Reactivity：Mouse
Applications：IHC
Concentration：0.87 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse CD11b
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC1：500
Swissprot：P05555,P46892
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells, Tags ＆ Cell Markers
