Background：The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components： a preexisting cytosolic component that translocates to the nucleus upon T cell receptor （TCR） stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms：cytoplasmic 4,NF ATc4,NF-AT3,NF-ATc4,NFAC4,NFAT3,NFATc4,Nuclear factor of activated T cells cytoplasmic 4,Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4,Nuclear factor of activated T-cells,T cell transcription factor NFAT3,T-cell transcription factor NFAT3
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：2mg/mL
Immunogen：Recombinant Human Nuclear factor of activated T-cells protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：IHC 1：100-1：400
Gene_ID（human）：4776
Swissprot：Q14934
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
