Background：CCNA2 belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1,which is present only in germ cells,this cyclin is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases,and thus promotes both cell cycle G1/S and G2/M transitions.
仕様
Synonyms：Cyclin A2,Cyclin-A,CCN1,CCNA,Cyclin-A2,Cyclin A.
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：2mg/mL
Immunogen：Recombinant Human Cyclin-A2 protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：IHC 1：100-1：400
Gene_ID（human）：890
Swissprot：P20248
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling
