Background：RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative abundance of microRNAs, when overexpressed. RBM3 enhances phosphoryaltion of translation initiation factors and active polysome formation. It is up-regulated in human tumors. RBM3 is a potential proto-oncogenic proteins upon overexpression.
仕様
Synonyms：2600016C11Rik,IS1 RNPL,MGC105811,MGC118410,Putative RNA binding protein 3,Putative RNA-binding protein 3,Rbm3,RBM3,RNA binding motif （RNP1, RRM） protein 3,RNA binding motif protein 3,RNA-binding motif protein 3,RNA-binding protein 3,RNPL,RP23-27I6.7
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：2mg/mL
Immunogen：Recombinant Human RNA-binding protein 3 protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：IHC 1：100-1：400
Gene_ID（human）：5935
Swissprot：P98179
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism
