Background：IFNAR1 （Interferon Alpha And Beta Receptor Subunit 1） is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include interferon receptor activity and type I interferon receptor activity. An important paralog of this gene is ENSG00000249624.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
仕様
Synonyms：Alpha type antiviral protein,Antiviral protein,alpha-type,Antiviral protein,beta-type,AVP,Beta type antiviral protein,CRF2-1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,IFN alpha REC,IFN alpha receptor,IFN alpha/beta Receptor alpha,IFN beta receptor,IFN Interferon-beta receptor,IFN-alpha/beta receptor 1,IFN-R-1,IFNAR,Ifnar1,IFNBR,IFRC,INAR1,Interferon （alpha beta and omega） receptor 1,interferon alpha and beta receptor subunit 1,Interferon alpha/beta receptor 1,Interferon alpha/beta receptor alpha chain,Interferon beta receptor 1,interferon receptor 1,Interferon-alpha receptor,Type I interferon receptor 1
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：0.5mg/mL
Immunogen：Recombinant Human Interferon alpha/beta receptor 1 protein
Purification Method：Antigen Affinity Purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：IHC 1：100-1：300
Gene_ID（human）：3454
Swissprot：P17181
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
