Background：Adiponectin （AdipoQ）,an adipocyte-derived hormone,is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes,including improving insulin sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood,but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans,including chicken testis,bovine ovary,and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors,AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle,whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth,angiogenesis and tissue remodeling by binding and sequestering various growth factors.
仕様
Synonyms：30 kDa adipocyte complement related protein,30 kDa adipocyte complement-related protein,ACDC,ACRP30,ADIPO,Adipocyte,Adipocyte C1q and collagen domain containing protein,Adipocyte complement related 30 kDa protein,Adipocyte complement related protein of 30 kDa,Adipocyte complement-related 30 kDa protein,adipocyte-specific secretory protein,Adiponectin,Adiponectin precursor,adiponectin,C1Q and collagen domain containing,Adipoq,Adipose most abundant gene transcript 1,Adipose most abundant gene transcript 1 protein,Adipose specific collagen like factor,ADIPQTL1,ADPN,APM 1,apM-1,APM1,C1q and collagen domain-containing protein,GBP28,Gelatin binding protein,Gelatin binding protein 28,Gelatin-binding protein
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：0.02mg/mL
Immunogen：Recombinant Mouse Adiponectin protein
Purification Method：Antigen Affinity Purification
Clonality：Polyclonal
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：WB 1：500-1：1000 IHC 1：100-1：300
Gene_ID（human）：11450
Swissprot：Q60994
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells
