Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:60B8Ag,AI323541,B8Ag,BEE11,CAGA,Calgranulin-A,Calprotectin L1L subunit,Calprotectin,included,CFAG,CGLA,Chemotactic cytokine CP-10,CP-10,Cystic fibrosis antigen,L1Ag,Leukocyte L1 complex light chain,MA387,MIF,Migration inhibitory factor-related protein 8,MRP-8,Myeloid-related protein 8,Neutrophil cytosolic 7 kDa protein,NIF,p8,Pro-inflammatory S100 cytokine,Protein S100-A8,S100 calcium binding protein A8 (calgranulin A),S100 calcium binding protein A8,S100 calcium-binding protein A8,S100A8,S100A8/S100A9 complex,included,S10A8,Urinary stone protein band A
Host:Rabbit
Reactivity:Human
Applications:IHC
Concentration:0.36mg/mL
Immunogen:Recombinant Human Protein S100-A8 protein
Purification Method:Affinity Purification
Clonality:Polyclonal
Buffer:PBS with 0.05% Proclin300, 50% glycerol, pH7.3.