Background：Periostin （POSTN,PN）,originally named as osteoblast-specific factor 2 （OSF-2）,is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.
仕様
Synonyms：Fasciclin-I like,MGC119510,MGC119511,OSF 2,OSF-2,OSF2,Osteoblast specific factor 2 （fasciclin I like）,Osteoblast specific factor 2,Osteoblast specific factor,Osteoblast-specific factor 2,PDLPOSTN,Periodontal ligament specific periostin,Periostin,Periostin isoform thy2,Periostin isoform thy4,Periostin isoform thy6,Periostin isoform thy8,Periostin osteoblast specific factor,PN,POSTN,POSTN,RP11 412K4.1
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：0.36mg/mL
Immunogen：Recombinant Human Periostin protein
Purification Method：Antigen Affinity Purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：WB 1：500-1：1000 IHC 1：100-1：200
Gene_ID（human）：10631
Swissprot：Q15063
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal Transduction, Tags and Cell Markers
