Background：Mucin-5ACis aproteinthat in humans is encoded by theMUC5ACgene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease （COPD）. Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
仕様
Synonyms：Apomucin,Apomucin Major Airway Glycoprotein,Gastric mucin,LeB,Lewis B blood group antigen,Major Airway Glycoprotein,MUC 5,MUC5,MUC5AC,Mucin 5 subtype AC tracheobronchial,Mucin 5 Subtypes A And C,Mucin 5 subtypes A and C tracheobronchial/gastric,Mucin 5,tracheobronchial/gastric,Mucin 5AC,Mucin 5AC oligomeric mucus/gel forming,Mucin 5AC,oligomeric mucus/gel forming pseudogene,Mucin,TBM,Tracheobronchial Mucin （TBM）,Tracheobronchial mucin
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：1mg/mL
Immunogen：Recombinant Human Mucin-5AC protein
Purification Method：Antigen Affinity Purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：IHC 1：100-1：400
Gene_ID（human）：4586
Swissprot：P98088
Isotype：IgG
Research Areas：Cancer, Immunology, Signal Transduction
