Background:RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis.
仕様
Synonyms:Androgen receptor associated protein 24,Androgen receptor-associated protein 24,ARA 24,ARA24,Gsp1,GTP binding nuclear protein RAN,GTP-binding nuclear protein Ran,GTPase Ran,Guanosine triphosphatase Ran,LPS,OK/SW-cl.81,ran,RAN member RAS oncogene family,RAN,RanGTPase,Ras like protein TC4,Ras related nuclear protein,Ras-like protein TC4,Ras-related nuclear protein,RASL2 8,TC 4,TC4
Host:Rabbit
Reactivity:Human,Rat,Mouse
Applications:WB
Concentration:2mg/mL
Immunogen:Recombinant Human GTP-binding nuclear protein Ran protein
Purification Method:Affinity Purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Dilution:WB 1:500-1:1000
Gene_ID(human):5901
Swissprot:P62826
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction