Background：This gene encodes a member of the tripartite motif （TRIM） family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey （muscle-liver-brain-eye） nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.
仕様
Synonyms：E3 ubiquitin protein ligase TRIM37,E3 ubiquitin-protein ligase TRIM37,KIAA0898,MUL,MUL protein,Mulibrey nanism gene,Mulibrey nanism protein,POB 1,POB1,RING B box coiled coil protein,TEF 3,TEF3,TRI37,TRIM 37,Trim37,Tripartite motif containing 37,Tripartite motif containing 37 protein,Tripartite motif containing protein 37,Tripartite motif-containing protein 37
