Background：This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission （EMPF）. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：DLP1,dnm1l,DNM1L,Dnm1p/Vps1p-like protein,dnml1,DRP1,DVLP,Dymple,Dynamin 1 like,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin like protein,Dynamin related protein 1,Dynamin-1-like protein,Dynamin-like protein 4,Dynamin-like protein,Dynamin-like protein IV,Dynamin-related protein 1,DYNIV 11,EMPF,EMPF1,FLJ41912,HdynIV,VPS1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：2mg/mL
Immunogen：Recombinant Human Dynamin-1-like protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB 1：500-1：2000
Gene_ID（human）：10059
Swissprot：O00429
Isotype：IgG
Research Areas：Cancer, Cell biology, Metabolism, Neuroscience, Signal transduction
