Background:This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
仕様
Synonyms:CMD1GG,DHSA_HUMAN,Flavoprotein subunit of complex II,Fp,PGL5,SDH 2,SDH1,SDHF,Succinate dehydrogenase [ubiquinone] flavoprotein subunit
Host:Rabbit
Reactivity:Human
Applications:WB,IHC
Concentration:2mg/mL
Immunogen:Recombinant Human Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial protien
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB 1:500-1:2000 IHC 1:50-1:200
Gene_ID(human):6389
Swissprot:P31040
Isotype:IgG
Research Areas:Cancer, Cell biology, Metabolism, Signal transduction, Tags and Cell markers