Background：The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
仕様
Synonyms：18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：2mg/mL
Immunogen：Recombinant human Homeobox protein Cofilin-1 protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
Dilution：WB 1：500-1：1000
Gene_ID（human）：1072
Swissprot：P23528
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience, Signal transduction
