Background：This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 （ASC-1） complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 （SMABF1）.
仕様
Synonyms：Activating signal cointegrator 1,ASC 1,ASC-1,HsT17391,Thyroid hormone receptor interactor 4,Thyroid receptor interacting protein 4,Thyroid receptor-interacting protein 4,TR-interacting protein 4,TRIP 4,TRIP-4,Trip4,TRIP4,ZC2HC5,Zinc finger C2HC5 type
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：2mg/mL
Immunogen：Recombinant human Activating signal cointegrator 1 protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
