Background：Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
仕様
Synonyms：Aimp2,AIMP2,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2,Aminoacyl tRNA synthetase complex interacting multifunctional protein 2,ARS interacting multi functional protein 2,JTV 1,JTV 1 protein,JTV1,JTV1 gene,Multisynthase complex auxiliary component p38,Multisynthetase complex auxiliary component p38,P38,PRO0992,Protein JTV 1,Protein JTV-1,tRNA SYNTHETASE COFACTOR p38
Host：Rabbit
Reactivity：Human,Rat
Applications：WB
Concentration：2mg/mL
Immunogen：Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
