Background：IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency （IGF1 deficiency） which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1A.
仕様
Synonyms：IBP1,IGF I,IGF IA,IGF IB,IGF-I,Igf1,IGF1,IGF1A,IGFI,IGFIA,Insulin like growth factor 1 （somatomedin C）,Insulin like growth factor 1,Insulin like growth factor IA,Insulin like growth factor IB,Insulin-like growth factor I,Mechano growth factor,MGF,OTTHUMP00000195080,OTTHUMP00000195081,OTTHUMP00000195082,OTTHUMP00000195083,OTTHUMP00000195084,Somatomedia C,Somatomedin C,Somatomedin-C
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：2mg/mL
Immunogen：Recombinant Human Insulin-like growth factor I protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC 1：50-1：100
Gene_ID（human）：3479
Swissprot：P05019
Isotype：IgG
Research Areas：Cancer, Developmental biology, Signal transduction
