Background：In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
仕様
Synonyms：Heat shock 70 kDa protein 1 antibody,HSP70 1,HSP70 1B,HSP70 2,HSP70-1/HSP70-2,HSP70-1A,HSP70.1/HSP70.2,HSPA1,HSPA1B
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：2mg/mL
Immunogen：Recombinant Mouse Heat shock 70 kDa protein 1B protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ Proclin300, 50％ glycerol, pH7.3.
