Background:Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.
仕様
Synonyms:CD 295,CD295,CD295 antigen,Db,Fa,HuB219,LEP R,LEP-R,LEPR,LEPR,LEPRD,Leptin receptor,Leptin receptor fatty,Leptin receptor gene related protein,Leptin receptor precursor,Leptin receptor precursor,OB R gene related protein,OB receptor,OB-R,OB-RGRP,obl,Obr
Host:Rabbit
Reactivity:Rat
Applications:IHC
Concentration:2mg/mL
Immunogen:Recombinant Rat Leptin protein
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Dilution:IHC 1:50-1:200
Gene_ID(human):25608
Swissprot:P50596
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction