特徴
- 背景：Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
仕様
- 種由来：Human/Mouse/Rat
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human/Mouse/Rat Growth Differentiation Factor 8 is produced by our Mammalian expression system and the target gene encoding Lys262-Ser375 is expressed.
- 別名（遺伝子名）：Growth/differentiation factor 8; GDF-8; Myostatin; Mstn; Gdf8
- アミノ酸配列：Lys262-Ser375
- アクセッションＮｏ．：O14793
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：13.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463611-elabscience-PKSR030542.pdf
- サイズ：50ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4055-13
Recombinant Human/Mouse/Rat GDF-8/Myostatin 50ug
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86-4051-64
Recombinant Human/Mouse/Rat GDF-8/Myostatin 10ug
|
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