特徴
- 背景：GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; Gas6; GAS-6; growth arrest-specific 6; growth arrest-specific protein 6
- アミノ酸配列：Ala31-Ala678
- アクセッションＮｏ．：Q14393
- タグ種類：C-6His
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：72.7 kDa
- 組成：Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
- 保存条件：Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463392-elabscience-PKSH033928.pdf
- サイズ：50ug
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4049-03
Recombinant Human GAS6 (C-6His) 10ug
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86-4053-94
Recombinant Human GAS6 (C-6His) 50ug
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