特徴
- 背景:Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
仕様
- 種由来:Human
- 発現宿主:Human Cells
- 純度:>95% as determined by reducing SDS-PAGE.
- 遺伝子構造:Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21 Asn132 is expressed with a Fc tag at the C-terminus.
- 別名(遺伝子名):Interleukin-13;IL-13;
- アミノ酸配列:Gly21 Asn132
- アクセッションNo.:AAK53823
- タグ種類:C-Fc
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- 分子量:39.2 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://u2.elabscience.com/viewpdf-463378-elabscience-PKSH033914.pdf
- サイズ:50ug
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-4048-58
Recombinant Human Interleukin-13/IL-13 (C-Fc) 10ug
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86-4052-52
Recombinant Human Interleukin-13/IL-13 (C-Fc) 50ug
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