特徴
- 背景:Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation.
仕様
- 種由来:Human
- 発現宿主:Human Cells
- 純度:>95% as determined by reducing SDS-PAGE.
- 遺伝子構造:Recombinant Human Atrial Natriuretic Peptide Receptor 3 is produced by our Mammalian expression system and the target gene encoding Thr24-Glu481 is expressed with a Fc tag at the C-terminus.
- 別名(遺伝子名):ANP-C; ANPR-C; NPR3; NPRC; NPR-C;ANPRC; C5orf23
- アミノ酸配列:Thr24-Glu481
- アクセッションNo.:P17342
- タグ種類:C-Fc
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- 分子量:77.5 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://u2.elabscience.com/viewpdf-463486-elabscience-PKSH034022.pdf
- サイズ:50ug
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4052-45
Recombinant Human NPRC/NPR3 (C-Fc) 50ug
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86-4048-45
Recombinant Human NPRC/NPR3 (C-Fc) 10ug
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