特徴
- 背景：Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play acentral role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be ahomologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequenceidentity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surfacechemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cellfusion and virus infection.
仕様
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
- 別名（遺伝子名）：C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309;CCL1; SCYA1
- アミノ酸配列：Lys24-Lys96
- アクセッションＮｏ．：P22362
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- 分子量：8.62 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-356342-elabscience-PKSH033809.pdf
- サイズ：50ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4052-33
Recombinant Human CCL1/I-309 Protein 50ug
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86-4048-65
Recombinant Human CCL1/I-309 Protein 10ug
|
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