特徴
- 背景:SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early response gene. Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence. SECTM1 proteins from human and mouse show species specific binding of CD7 and co stimulation of T cells, including enhancement of CD3 induced proliferation.
仕様
- 種由来:Mouse
- 発現宿主:Human Cells
- 純度:>95% as determined by reducing SDS-PAGE.
- 遺伝子構造:Recombinant Mouse Secreted And Transmembrane Protein 1A is produced by our Mammalian expression system and the target gene encoding Gln28Thr165 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):SECTM1A; Sectm1a
- アミノ酸配列:Gln28Thr165
- アクセッションNo.:A2ABP9
- タグ種類:C-6His
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- 分子量:16.2 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://u2.elabscience.com/viewpdf-463546-elabscience-PKSM041413.pdf
- サイズ:50ug
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4052-28
Recombinant Mouse SECTM1A (C-6His) 50ug
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86-4048-31
Recombinant Mouse SECTM1A (C-6His) 10ug
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