特徴
- 背景：The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
仕様
- 種由来：Human
- 発現宿主：E.coli
- 純度：>90% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human Nuclear Factor NF-kappa-B P50 Subunit is produced by our E.coli expression system and the target gene encoding Met1-Gly434 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- アミノ酸配列：Met1-Gly434
- アクセッションＮｏ．：P19838-2
- タグ種類：N-6His
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：49.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20mM GSH, pH 8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463418-elabscience-PKSH033954.pdf
- サイズ：50ug
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| 商品イメージ | アズワン品番 商品名 |
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86-4048-09
Recombinant Human NFKB1 (N-6His) 10ug
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86-4052-08
Recombinant Human NFKB1 (N-6His) 50ug
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