86-4050-64 Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated 20ug PKSH034043
[Elabscience]
特徴
- 背景：Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Biotinylated Recombinant Human Dickkopf-related protein 1 is produced by our Mammalian expression system and the target gene encoding Thr32-His266 is expressed with a Avi, 6His tag at the C-terminus.
- 別名（遺伝子名）：Dickkopf-related protein 1; Dickkopf-1; Dkk-1
- アミノ酸配列：Thr32-His266
- アクセッションＮｏ．：O94907
- タグ種類：C-Avi-6His
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：28.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463507-elabscience-PKSH034043.pdf
- サイズ：20ug
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| 商品イメージ | アズワン品番 商品名 |
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86-4050-64
Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated 20ug
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86-4054-53
Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated 100ug
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