86-4050-54 Recombinant Human SLAM Family Member 5/SLAMF5/CD84(C-6His-Avi) Biotinylated 20ug PKSH034005
[Elabscience]
特徴
- 背景：SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Biotinylated Recombinant Human SLAM Family Member 5 is produced by our Mammalian expression system and the target gene encoding Lys22-Arg220 is expressed with a 6His, Avi tag at the C-terminus.
- 別名（遺伝子名）：SLAM family member 5; Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD84; SLAMF5
- アミノ酸配列：Lys22-Arg220
- アクセッションＮｏ．：Q9UIB8
- タグ種類：C-6His-Avi
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：24.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463469-elabscience-PKSH034005.pdf
- サイズ：20ug
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-4054-43
Recombinant Human SLAM Family Member 5/SLAMF5/CD84(C-6His-Avi) Biotinylated 100ug
|
|
|
86-4050-54
Recombinant Human SLAM Family Member 5/SLAMF5/CD84(C-6His-Avi) Biotinylated 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|