86-4050-52 Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated 20ug PKSH034003
[Elabscience]
特徴
- 背景：Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>90% as determined by reducing SDS-PAGE.
- 遺伝子構造：Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
- 別名（遺伝子名）：Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
- アミノ酸配列：Gln30-Gly254
- アクセッションＮｏ．：O00481
- タグ種類：C-Fc-Avi
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：52.6 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463467-elabscience-PKSH034003.pdf
- サイズ：20ug
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