背景:T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
仕様
種由来:Human
発現宿主:Human Cells
純度:>95% as determined by reducing SDS-PAGE.
遺伝子構造:Recombinant Human CD3D&CD3E is produced by our Mammalian expression system and the target gene encoding Phe22-Ala105&Asp23-Asp126 is expressed with a Fc-Flag, Fc-6His tag at the C-terminus.
エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
分子量:37&39.2 kDa
組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.