背景:Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
仕様
種由来:Human
発現宿主:Human Cells
純度:>95% as determined by reducing SDS-PAGE.
遺伝子構造:Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a Fc tag at the C-terminus.
別名(遺伝子名):Butyrophilin Subfamily 1 Member A1; BT; BTN1A1; BTN
アミノ酸配列:Ala27-Arg242
アクセッションNo.:Q13410
タグ種類:C-Fc
エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
分子量:50.8 kDa
組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.