背景:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
仕様
種由来:Rat
発現宿主:E.coli
純度:>85 % as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding the Rat KLK10 (P36375-1) (Pro19-Pro259) was expressed with a polyhistidine tag at the N-terminus.
別名(遺伝子名):Breast normal epithelial cell associated serine protease;Kallikrein related peptidase 10;Kallikrein10;KLK 10;KLK10;NES 1;NES1;Normal epithelial cell-specific 1;Protease serine like 1;Protease serine-like 1;PRSS L1;PRSSL 1;PRSSL1
アミノ酸配列:Pro19-Pro259
アクセッションNo.:P36375-1
タグ種類:N-His
エンドトキシン濃度:Not tested.
分子量:27.05 kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.