背景:Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity). Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis. Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors.Plays a role in immune response, of T-cells, natural killer (NK) and neutrophils.
仕様
種由来:Mouse
発現宿主:E.coli
純度:>90% as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding the Mouse Ceacam1/BGP-1 protein (P31809) (35E-416P) was expressed with a polyhistidine tag at the N-terminus.
保存条件:Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.