背景:Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9–K23,and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1–K8,and the hair keratins,Hb1–Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.
仕様
種由来:Mouse
発現宿主:E.coli
純度:>95 % as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding the Mouse KRT7 (Q9DCV7-1) (Gln80-Thr375) was expressed with a polyhistidine tag at the N-terminus.
別名(遺伝子名):CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7;K7;Keratin 7;Keratin 7;type II;Keratin type II cytoskeletal 7;Keratin;55K type II cytoskeletal;Keratin;simple epithelial;Keratin;simple epithelial type I;K7;Keratin;type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
アミノ酸配列:Gln80-Thr375
アクセッションNo.:Q9DCV7-1
タグ種類:N-His
エンドトキシン濃度:Not tested.
分子量:34.1 kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.