背景:IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions,including T cell proliferation,interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
仕様
種由来:Mouse
発現宿主:E.coli
純度:>90 % as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding the Mouse IL2 (P04351-1) (Ala21-Gln169) was expressed with a polyhistidine tag at the N-terminus.
別名(遺伝子名):Aldesleukin;IL 2;IL-2;IL2;IL2;Interleukin 2;Interleukin-2;Involved in regulation of T cell clonal expansion;Lymphokine;OTTHUMP00000164090;POIL2;T Cell Growth Factor;T-cell growth factor;TCGF
アミノ酸配列:Ala21-Gln169
アクセッションNo.:P04351-1
タグ種類:N-His
エンドトキシン濃度:Not tested.
分子量:17.2 kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.