背景:Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
仕様
種由来:Human
発現宿主:E.coli
純度:>90% as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding theHuman CD74 protein (P04233) (73Q-296M) was expressed with a polyhistidine tag at the N-terminus.
別名(遺伝子名):CD 74,CD74 antigen (invariant polypeptide of major histocompatibility complex,class II antigen-associated),CD74 molecule,CD74 molecule,major histocompatibility complex,class II invariant chain,CLIP,DHLAG,Gamma chain of class II antigens,HG2A,HLA class II histocompatibility antigen gamma chain,HLA DR antigens associated invariant chain,HLA DR gamma,HLA-DR antigens-associated invariant chain,HLA-DR-gamma,HLADG,HLADR antigens associated invariant chain,Ia antigen associated invariant chain,Ia antigen-associated invariant chain,Ia associated invariant chain,Ia gamma,Ii,Invariant polypeptide of major histocompatibility complex class II antigen associated,la-gamma,Major histocompatibility complex class II invariant chain,MHC HLA DR gamma chain,MHC HLA-DR gamma chain,p33,p35,Protein 41
アミノ酸配列:73Q-296M
アクセッションNo.:P04233
タグ種類:N/C-His
エンドトキシン濃度:Not tested.
分子量:26.6kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.