背景:Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
仕様
種由来:Human
発現宿主:E.coli
純度:>90 % as determined by reducing SDS-PAGE.
遺伝子構造:A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.
別名(遺伝子名):BBC 3, Bbc3, BBC3_HUMAN, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1
アミノ酸配列:1M-193N
アクセッションNo.:Q9BXH1-1
タグ種類:N-His
エンドトキシン濃度:Not tested.
分子量:20.1kDa
組成:Supplied as sterile Tris,EDTA,PH 8.0.
保存条件:Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.