背景：The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
種由来：Human
発現宿主：E.coli
純度：>90 % as determined by reducing SDS-PAGE.
遺伝子構造：A DNA sequence encoding the Human S100A8 (P05109-1) (Met1-Glu93) was expressed with a polyhistidine tag at the N-terminus.
別名（遺伝子名）：60B8Ag;AI323541;B8Ag;BEE11;CAGA;Calgranulin-A;Calprotectin L1L subunit;Calprotectin;included;CFAG;CGLA;Chemotactic cytokine CP-10;CP-10;Cystic fibrosis antigen;L1Ag;Leukocyte L1 complex light chain;MA387;MIF;Migration inhibitory factor-related protein 8;MRP-8;Myeloid-related protein 8;Neutrophil cytosolic 7 kDa protein;NIF;p8;Pro-inflammatory S100 cytokine;Protein S100-A8;S100 calcium binding protein A8 (calgranulin A);S100 calcium binding protein A8;S100 calcium-binding protein A8;S100A8;S100A8/S100A9 complex;included;S10A8;Urinary stone protein band A
アミノ酸配列：Met1-Glu93
アクセッションＮｏ．：P05109-1
タグ種類：N-His
エンドトキシン濃度：Not tested.
分子量：10.83 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
