背景：Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.
仕様
種由来：Human
発現宿主：E.coli
純度：>85 % as determined by reducing SDS-PAGE.
遺伝子構造：A DNA sequence encoding the Human POSTN (Q15063-1) (Ala21-Leu365) was expressed with a polyhistidine tag at the N-terminus.
別名（遺伝子名）：Fasciclin-I like;MGC119510;MGC119511;OSF 2;OSF-2;OSF2;Osteoblast specific factor 2 (fasciclin I like);Osteoblast specific factor 2;Osteoblast specific factor;Osteoblast-specific factor 2;PDLPOSTN;Periodontal ligament specific periostin;Periostin;Periostin isoform thy2;Periostin isoform thy4;Periostin isoform thy6;Periostin isoform thy8;Periostin osteoblast specific factor;PN;POSTN;POSTN;RP11 412K4.1
アミノ酸配列：Ala21-Leu365
アクセッションＮｏ．：Q15063-1
タグ種類：N-His
エンドトキシン濃度：Not tested.
分子量：38 kDa
組成：Lyophilized from sterile 20mM Tris,1mM EDTA, pH 7.4
保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
