特徴
- 背景：Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 6 is produced by our Mammalian expression system and the target gene encoding Pro134-Leu281 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：apoptosis (APO-1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1CD95L; APTL; CD178 antigen; CD178; CD95L; CD95-L; Fas antigen ligand; Fas ligand (TNF superfamily, member 6); Fas Ligand; FASLCD95 ligand; FASLG; TNFSF6
- アミノ酸配列：Pro134-Leu281
- アクセッションＮｏ．：P48023
- タグ種類：N-6His
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：17.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463350-elabscience-PKSH033886.pdf
- サイズ：10ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4048-85
Recombinant Human Fas Ligand / TNFSF6 (N-6His) 10ug
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86-4052-68
Recombinant Human Fas Ligand / TNFSF6 (N-6His) 50ug
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