86-4048-12 ［取扱停止］Recombinant Human CXCR4 (C28A) Protein (His Tag) 20ug PKSH500022
[Elabscience]
特徴
- 背景：Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.
仕様
- 種由来：Human
- 発現宿主：E.coli
- 純度：>95 % as determined by reducing SDS-PAGE.
- 遺伝子構造：A DNA sequence encoding the human CXCR4 (C28A) (1M-38K) was expressed with a GST tag at the N-terminus.
- 別名（遺伝子名）：C-X-C chemokine receptor type 4, CD184, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, NPYR, SDF 1 receptor, WHIM
- アミノ酸配列：1M-38K
- アクセッションＮｏ．：P61073
- タグ種類：N-GST
- エンドトキシン濃度：Not tested.
- 分子量：31.2kDa
- 組成：Lyophilized from sterile potassium phosphate, pH 7.4
- 保存条件：Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463622-elabscience-PKSH500022.pdf
- サイズ：20ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4051-37
Recombinant Human CXCR4 (C28A) Protein (His Tag) 100ug
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86-4048-12
Recombinant Human CXCR4 (C28A) Protein (His Tag) 20ug
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