特徴
- 背景:Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.
仕様
- 種由来:Human
- 発現宿主:Human Cells
- 純度:>95% as determined by reducing SDS-PAGE.
- 遺伝子構造:Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.
- 別名(遺伝子名):AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1
- アミノ酸配列:Asp256-Phe498
- アクセッションNo.:Q15389
- タグ種類:N-Fc
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- 分子量:53.9 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://u2.elabscience.com/viewpdf-463419-elabscience-PKSH033955.pdf
- サイズ:10ug
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-4051-80
Recombinant Human Angiopoietin-1/ANG1 (N-Fc) 50ug
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86-4047-79
Recombinant Human Angiopoietin-1/ANG1 (N-Fc) 10ug
|
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