86-4047-78 ［取扱停止］Recombinant Human Interleukin-35/IL-35 (C-Fc) 10ug PKSH033974
[Elabscience]
特徴
- 背景：Interleukin-35 is a newest and potent suppressive cytokine of the IL-12 family. Unlike other members of the IL-12 family which are produced mainly by antigen-presenting cells (APCs), IL-35 has been identified as a potentially immunosuppressive cytokine primarily produced by regulatory T (Treg) cells, and to a lesser extent by activated dendritic cells and macrophages. IL-35 is composed of the IL-12 p35 subunit and the IL-27 Epstein–Barr virus-induced protein 3 (EBI3) subunit. IL-35 plays an important role in many disease models and has been recently shown to have additional functions aside from inhibition of proliferation, including inducing its own expression in non-Treg cells.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>90% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human Interleukin-35 is produced by our Mammalian expression system and the target gene encoding Arg23-Ser219&Arg21-Lys229 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Interleukin 35; IL35; hIL35
- アミノ酸配列：Arg23-Ser219&Arg21-Lys229
- アクセッションＮｏ．：P29459&Q14213
- タグ種類：C-Fc
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：73.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463438-elabscience-PKSH033974.pdf
- サイズ：10ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4051-48
Recombinant Human Interleukin-35/IL-35 (C-Fc) 50ug
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86-4047-78
Recombinant Human Interleukin-35/IL-35 (C-Fc) 10ug
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