特徴
- 背景：CD81, also known as TAPA-1 and Tetraspanin-28, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. CD81 associates with a wide range of membrane proteins including CD151, TfR2, LDL R, PCSK9, Glypican 3, IFITM1, IGSF8/CD316, FPRP, and complexes of CD19-CD21. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. CD81 additionally functions as a receptor for the E2 glycoprotein of hepatitis C virus. The CD81-E2 interaction inhibits NK cell cytolytic activity, provides a co-stimulatory signal to T cells, and inhibits the maturation of plasmacytoid dendritic cells.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human CD81 antigen is produced by our Mammalian expression system and the target gene encoding Phe113-Lys201 is expressed with a Fc tag at the N-terminus.
- 別名（遺伝子名）：CD81 antigen; CD81 molecule; CD81; CVID6; TAPA1; TAPA-1; TSPAN28
- アミノ酸配列：Phe113-Lys201
- アクセッションＮｏ．：P60033
- タグ種類：N-Fc
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：36.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463473-elabscience-PKSH034009.pdf
- サイズ：10ug
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| 商品イメージ | アズワン品番 商品名 |
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86-4047-69
Recombinant Human CD81 (N-FC) 10ug
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86-4051-67
Recombinant Human CD81 (N-FC) 50ug
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