86-4047-67 Recombinant Human Angiopoietin-related Protein 3/ANGPTL3 (C-Fc) 10ug PKSH033975
[Elabscience]
特徴
- 背景：Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. ANGPTL3 promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 expression in vivo is up-regulated by LXR agonists and down-regulated by insulin, leptin, and agonists of TRβ or PPARβ.
仕様
- 種由来：Human
- 発現宿主：Human Cells
- 純度：>95% as determined by reducing SDS-PAGE.
- 遺伝子構造：Recombinant Human Angiopoietin-related Protein 3 is produced by our Mammalian expression system and the target gene encoding Ser17-Pro220 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Angiopoietin-related protein 3; ANGPTL3; Angiopoietin-5; ANG-5; Angiopoietin-like protein 3; ANGPT5
- アミノ酸配列：Ser17-Pro220
- アクセッションＮｏ．：Q9Y5C1
- タグ種類：C-Fc
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- 分子量：50.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-463439-elabscience-PKSH033975.pdf
- サイズ：10ug
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| 商品イメージ | アズワン品番 商品名 |
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86-4047-67
Recombinant Human Angiopoietin-related Protein 3/ANGPTL3 (C-Fc) 10ug
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86-4051-65
Recombinant Human Angiopoietin-related Protein 3/ANGPTL3 (C-Fc) 50ug
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