86-4045-97　［取扱停止］Phospho- beta -catenin(S33/S37/T41) Polyclonal Antibody 200uL　E-AB-68169

特徴

• 背景：The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

仕様

• 抗体タイプ：Phosphorylated antibody
• アプリケーション：WB,IHC
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000 IHC 1:50-1:200
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391421-Elabscience-E-AB-68169.pdf
• サイズ：200uL
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