86-4045-82　［取扱停止］Phospho-ZAP70(Y493) Polyclonal Antibody 200uL　E-AB-68154

特徴

• 背景：This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

仕様

• 抗体タイプ：Phosphorylated antibody
• アプリケーション：WB,IHC
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 抗原：A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70
• 緩衝液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• 精製方法：Affinity purification
• 希釈倍率：WB 1:2000-1:5000 IHC 1:50-1:100
• 標識：Unconjugated
• メーカーマニュアル：https://file.elabscience.com/viewpdf-391406-Elabscience-E-AB-68154.pdf
• サイズ：200uL
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